10,11-Bis-(hydroxyalkyl) derivatives of cyproheptadine

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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26029362, C07D21170

Patent

active

040441431

ABSTRACT:
10,11-Furo and 10,11-bis-(hydroxyalkyl) derivatives of cyproheptadine are disclosed having anticholinergic activity but with diminished or eliminated antiserotonin and antihistamine activity. Also disclosed are processes for the preparation of such compounds; pharmaceutical compositions comprising such compounds, and methods of treatment comprising administering such compounds and compositions.

REFERENCES:
patent: 3014911 (1961-12-01), Engelhardt
patent: 3390179 (1968-06-01), Hucker et al.
patent: 3470188 (1969-09-01), Kaiser et al.
patent: 3625942 (1971-12-01), Edenhofer et al.
patent: 3660389 (1972-05-01), Hucker et al.
patent: 3838123 (1974-09-01), Viterbo et al.
patent: 3838174 (1974-09-01), Houlihan et al.

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