10,11,15-Trihydroxyprostanoic acid

Details 10,11,15-Trihydroxyprostanoic acid 10,11,15-Trihydroxyprostanoic acid

1973-12-07

1976-01-20

Gerstl, Robert

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602472R, 260268R, 2602936S, 2603212, 2605011, 26050117, 260514D, C07C 6138, C07C 6974

Patent

active

039338908

ABSTRACT:
Cyclopentane derivatives of the formula: ##SPC1##
(wherein the R symbols represent hydrogen or alkyl, n represents 4 or 6, and the symbols A, B, X and Y have any one of the following combinations: (a) A represents methylene, B represents hydroxymethylene, X represents ethylene and Y represents hydroxymethylene; (b) A represents carbonyl, B represents methylene, X represents ethylene or trans-vinylene and Y represents hydroxymethylene or carbonyl; or (c) A represents hydroxymethylene, B represents methylene, X represents ethylene or trans-vinylene and Y represents hydroxymethylene) are new compounds, possessing pharmacological properties, in particular, the production of hypotension, bronchodilatation, inhibition of gastric acid secretion and stimulation of uterine contraction.

REFERENCES:
patent: 3846475 (1974-11-01), Crabbe et al.
Crabbe et al., J. C. S. 119 (1973).

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