1α-Hydroxyvitamin D5, its synthesis and use in cancer...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 9,10-seco- cyclopentanohydrophenanthrene ring system doai

Reexamination Certificate

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C552S653000

Reexamination Certificate

active

06900191

ABSTRACT:
A compound of formula I:wherein R1 is hydrogen, R2 is —CH3, R3 is —CH3, and R4 is hydrogen, useful in cancer prevention and therapy.

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Mehta, R.G.; Moriarty, R.M.; Mehta, R.R.; Penmasta, R.; Lazzaro, G.; Constantinou, A.; and Guo, L.;Prevention of Preneoplastic Mammary Lesion Development by a Novel Vitamin D Analogue, 1α-Hydroxyvitamin D5, Feb. 5, 1997,Journal of the National Cancer Institute,vol. 89, No. 3, pp. 212-218.

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