1′-[4-[1-(4-fluorophenyl)-1H-indole-3-yl]-1-butyl]-sp...

Details 1′-[4-[1-(4-fluorophenyl)-1H-indole-3-yl]-1-butyl]-sp... 1′-[4-[1-(4-fluorophenyl)-1H-indole-3-yl]-1-butyl]-sp...

2005-01-18

2005-01-18

Morris, Patricia L. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S018000

Reexamination Certificate

active

06844352

ABSTRACT:
The present invention relates to a hydrohalogenide of 1′-[4-[1-(4-fluorophenyl)-1H-indole-3-yl]-1-butyl]-spiro[isobenzofuran-1(3H),4′-piperidine], pharmaceutical compositions containing the acid addition salts and the use thereof for the treatment of psychic and neurological disorders.

REFERENCES:
patent: 5665725 (1997-09-01), Moltzen et al.
patent: 9222554 (1992-12-01), None
Ejner K. Moltzen, et al.,J. Med. Chem.28: 2009-2017 (1995).
Jens Perregaard et al., “σ Ligands with Subnanomolar Affinity and Preference for the σ2Binding Site 1.3-ω Aminoalkyl)-1H-indoles,”J. Med. Chem.38: 1998-2008 (1995).

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