1-(Substituted) piperazine-4-benzenesulfinamides, compositions a

Details 1-(Substituted) piperazine-4-benzenesulfinamides, compositions a 1-(Substituted) piperazine-4-benzenesulfinamides, compositions a

1979-03-29

1984-01-10

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544360, 544383, A61K 31495, C07D29500, C07D40112

Patent

active

044253427

ABSTRACT:
Benzenesulfinamides of the formula ##STR1## wherein R is pyridyl, phenyl or phenyl substituted by halogen, loweralkyl, loweralkoxy or trifluoromethyl and the pharmaceutically acceptable acid addition salts thereof are useful blood pressure reducing agents.

REFERENCES:
patent: 3464971 (1969-09-01), Weaver et al.
patent: 3506649 (1970-04-01), Wei et al.
patent: 3980787 (1976-09-01), Klioze et al.
patent: 4015004 (1977-03-01), Klioze et al.
Wolff, Burger's Medicinal Chemistry, 4th Ed., Part I, The Basis of Medicinal Chemistry, pp. 108-111, 169-171.
Burger, Medicinal Chemistry, Third Ed., Part I, pp. 50-53.
S. S. Klioze et al., J. Med. Chem. 21, 400, 1978.

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