1 '-(substituted)ethyl-7.beta.-[2-(2-aminothiazol-4-yl)acetamido

Details 1 '-(substituted)ethyl-7.beta.-[2-(2-aminothiazol-4-yl)acetamido 1 '-(substituted)ethyl-7.beta.-[2-(2-aminothiazol-4-yl)acetamido

1984-06-01

1988-07-05

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D50136, A61K 31545

Patent

active

047555980

ABSTRACT:
A compound of the formula: ##STR1## wherein R is 2-methylpropyl, 2,2-dimethylpropyl, 1-ethylpropyl, 1-methylbutyl, 2-methylbutyl, 3-methylbutyl, n-pentyl, an alkyl group of 6 or 7 carbon atoms, or an alkenyl group of 2 to 7 carbon atoms, or a pharmaceutically acceptable salt thereof and processes for preparing the same are provided. The compound can orally be applied as antibiotics having improved absorbability.

REFERENCES:
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patent: 4189479 (1980-02-01), Kakeya et al.
patent: 4497809 (1985-02-01), Yoshimura et al.
Nakao et al., "7 Methoxycephalosporine Compounds . . . ," Chem. Abst. 92:146752(t), 1980.
Takahashi et al., " . . . Cephalosporanates," Chem. Abst. 78:124612(f) 1973.
Takahashi, et al., " . . . Desacetoxy Cephalosporanates," Chem. Abst. 78:124613(g) 1973.
Takahashi et al., " . . . Cephalosporanates," Chem. Abst. 78:111337(v) 1972.
Takeda Ind., Chem. Abstracts vol. 97 (1982), entry 144673x.

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