Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1985-12-09
1988-02-23
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546156, A61K 3147, C07D21556, C07D21558
Patent
active
047270802
ABSTRACT:
The present invention relates to new 1-substituted derivatives of 6-fluoro-7-(pyrrol-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, their preparation and their application as drugs.
The 1-substituted derivatives of 6-fluoro-7-(pyrrol-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid according to the invention correspond to the general formula I: ##STR1## in which: R represents a methyl radical, a 2-hydroxyethyl radical, a vinyl radical, a cyclopropylmethyl radical, a propyl radical, a cyclopropyl radical, a 2-fluoroethyl radical, a methylamino radical or an ethylamino radical, as well as their physiologically acceptable alkali metal or alkaline earth metal salts.
They are useful as antimicrobial agents, in particular as antibacterial and fungistatic agents.
REFERENCES:
patent: 4292317 (1981-09-01), Pesson
patent: 4398029 (1983-08-01), Irikura et al.
patent: 4499091 (1985-02-01), Wentland et al.
patent: 4552882 (1985-11-01), Esteve-Soler
patent: 4563459 (1986-01-01), Grohe et al.
patent: 4571396 (1986-02-01), Hutt et al.
patent: 4636506 (1987-01-01), Gilligan et al.
Artico et al., Il Farmaco, Ed. Sci., vol. 39, No. 11, pp. 910-924 (Nov. 1984).
Stefancich et al., Chemical Abstracts, vol. 102, 218189q (06/24/85).
Artico et al., Chemical Abstracts, vol. 102, p. 386, No. 21077v (1985).
Daus Donald G.
Provesan S.A.
Rivers Diana G.
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