1-(Substituted-aminoalkyl)-3-benzoyl-4-hydroxy-4-phenylpiperidin

Details 1-(Substituted-aminoalkyl)-3-benzoyl-4-hydroxy-4-phenylpiperidin 1-(Substituted-aminoalkyl)-3-benzoyl-4-hydroxy-4-phenylpiperidin

1975-06-16

1976-06-22

Winters, Sherman D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26029369, 26029371, 26029378, 424267, C07D21152

Patent

active

039651045

ABSTRACT:
1-(Substituted-aminoalkyl)-3-benzoyl-4-hydroxy-4-phenylpiperidines and related compounds having anti-arrhythmic activity are described herein. The 3-benzoyl compounds can be prepared by condensing the appropriate diamine with acetophenone and formaldehyde. The related 3-(.alpha.-hydroxybenzyl) compounds are prepared by reduction of the corresponding 3-benzoyl compounds.

REFERENCES:
Tomcufcik et al., C.A. 68: 95,699a, (1968).

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