1-(Substituted-aminoalkoxyphenyl)-2-methylene-1-alkanones, compo

Details 1-(Substituted-aminoalkoxyphenyl)-2-methylene-1-alkanones, compo 1-(Substituted-aminoalkoxyphenyl)-2-methylene-1-alkanones, compo

1982-05-19

1983-06-28

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424263, 424267, 424274, 544174, 546206, 546237, 546340, 548571, C07D29510, A61K 31535

Patent

active

043905374

ABSTRACT:
1-(Substituted-aminoalkoxyphenyl)-2-methylene-1-alkanones, a class of compounds possessing anti-allergic properties for use in the treatment of allergic conditions, such as asthma prepared by etherifying an alkanoylphenol with an aminoalkyl halide, converting the ether formed to a salt of Mannich base by reacting it with a salt of a secondary amine in the presence of formaldehyde or paraformaldehyde and treating the Mannich salt with a weak base to deaminate the same and form the final product.

REFERENCES:
Schultz, et al., Chemical Abstracts, vol. 73, No. 109,499e, (1970).

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