1-Substituted amino-2-alkyl-5-hydroxy-7,8-cyclopentano[h]-1,2,3,

Details 1-Substituted amino-2-alkyl-5-hydroxy-7,8-cyclopentano[h]-1,2,3, 1-Substituted amino-2-alkyl-5-hydroxy-7,8-cyclopentano[h]-1,2,3,

1974-03-28

1976-04-27

Gallagher, R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260287D, 260289R, 424258, C07D21702

Patent

active

039534588

ABSTRACT:
2-Alkyl-7,8-cyclopentano[h]-1,2,3,4-tetrahydroisoquinolines of the formula ##SPC1##
Wherein R is an aryl-lower alkyl amino group, an aryl-lower alkyl imino group, a diaryl-lower alkyl amino group or a diaryl-lower alkyl imino group, R.sub.1 is hydrogen or a lower alkyl group and R.sub.2 is a lower alkyl group, and acid addition salts and quaternary ammonium salts thereof, and the use of such compounds in pharmaceutical compositions to lower blood pressure in hypertensive animals.

REFERENCES:
morrison et al., Organic Chemistry, 2nd Ed., (1969), p. 734.
Morrison et al., Organic Chemistry, 2nd Ed., (1969), p. 567.
Burger, Medicinal Chemistry, 2nd Ed., (1960), pp. 42 & 497.

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