1-substituted-4-nitroimidazole compound and process for...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C548S327100

Reexamination Certificate

active

10523008

ABSTRACT:
The present invention relates to a 1-substituted-4-nitroimidazole compound represented by the general formula (1) or a salt thereof,(wherein R is a hydrogen atom, a lower alkoxy group-substituted lower alkyl group, a phenyl-lower alkoxy group-substituted lower alkyl group, a cyano-substituted lower alkyl group, a phenyl-lower alkyl group which may have lower alkoxy groups as the substituents in the phenyl ring or a group of the formula —CH2RA; X is a halogen atom or a group of the formula —S(O)n—R1) and method for preparing the same. The compound of the formula (1) is a useful compound as an intermediate for synthesis of various pharmaceutical and agricultural chemicals, particularly, as intermediates for antitubercular agents.

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Hoffer, CA 68:21933, 1968.
Nagarajan et al., CA 101:211044, 1984.
Suwinski et al.; “Nitroimidazoles. Part V. Chloronitroimidazoles From Dinitroimidazoles, A Reinvestigation”; Polish Journal of Chemistry, (Formerly Roczniki Chemii), vol. 56, pp. 1261-1272, ( 1982).

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