1-Substituted-3-amino-pyrazol-5-ones

Details 1-Substituted-3-amino-pyrazol-5-ones 1-Substituted-3-amino-pyrazol-5-ones

1975-12-04

1977-12-06

Moyer, Donald B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424273P, C07D23138, A61K 31415

Patent

active

040616533

ABSTRACT:
1-Substituted-3-amino-pyrazol-5-ones of the formula ##STR1## or a pharmaceutically acceptable non-toxic salt thereof wherein R is A. PHENYL SUBSTITUTED BY ONE OR TWO IDENTICAL OR DIFFERENT SUBSTITUENTS SELECTED FROM THE GROUP CONSISTING OF ALKYL, PHENYL, TRIFLUOROMETHYL, TRIFLUOROMETHOXY, NITRO, CYANO, FLUORO, BROMO, IODO, LOWER ALKYLAMINO, A CARBONAMIDO MOIETY OF THE FORMULA ##STR2## and a sulphonamido moiety of the formula ##STR3## wherein R.sub.1 and R.sub.2 are each hydrogen or straight or branched chain alkyl of 1 to 4 carbon atoms, or R.sub.1 and R.sub.2 together with the nitrogen atom to which they are attached may be linked together to form a 5-, 6- or 7-membered heterocyclic ring wherein the nitrogen atom is the only heteroatom or wherein oxygen is also present as a ring member;

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