1-Substituted-3,4-epoxypyrrolidines

Details 1-Substituted-3,4-epoxypyrrolidines 1-Substituted-3,4-epoxypyrrolidines

1979-01-09

1980-10-28

Tovar, Jose

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fungus, except allergen, or component thereof or substance...

2603265B, C07D29502, C07D20900

Patent

active

042307180

ABSTRACT:
3,4-Epoxypyrrolidines substituted in the 1-position with alkyl, cycloalkyl and phenylalkyl are disclosed which have pharmaceutical application in cataract prevention in animals and as intermediates in preparation of trans-3-aryloxy-4-hydroxypyrrolidines. The epoxypyrrolidines are prepared by a novel route involving chlorination of pyrrolines in aqueous medium.

REFERENCES:
patent: 3657274 (1972-04-01), Ohki et al.

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