Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-05-23
1994-03-22
Higel, Floyd D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514401, 514400, 5483355, 5483401, 5483481, 5483491, 546278, C07D23324, C07D23360, C07D23361, C07D40106, A61K 31415, A61K 3144
Patent
active
052964930
ABSTRACT:
The present patent application discloses compounds of the formula ##STR1## wherein R.sup.1 is C.sub.1-10 saturated or unsaturated alkyl; or ##STR2## wherein R'" is H or ##STR3## R.sup.2 is phenyl which is unsubstituted or substituted one or more times with halogen, CF.sub.3, C.sub.1-6 -alkoxy, NO.sub.2, CO.sub.2 --C.sub.1-6 -alkyl, methyl; benzyl which may be substituted one or more times with halogen, CF.sub.3, C.sub.1-6 -alkoxy, NO.sub.2, CO.sub.2 --C.sub.1-6 -alkyl, methyl; pyridyl; or cyclohexyl;
REFERENCES:
B. K. Siesjo et al., Journal of Cerebral Blood Flow and Metabolism, 9, 127-140 (1989).
B. K. Siesjo, NIPS, 5, 120-125 (1990).
Winifred G. Nayler, Calcium Antagonists, Academic Press, pp. 259, and 293-297 (1988).
Merck Index (11th Edition), entry 709 on p. 107 (1989).
Moldt Peter
Nielsen Elsebet O.
Higel Floyd D.
Hueschen Gordon W.
NeuroSearch A/S
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