1-Substituted-2-(2-pyridinyl)ethanone N-oxides

Details 1-Substituted-2-(2-pyridinyl)ethanone N-oxides 1-Substituted-2-(2-pyridinyl)ethanone N-oxides

1977-08-16

1978-08-01

Randolph, John D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D21389

Patent

active

041042743

ABSTRACT:
1-Substituted-2-(2-pyridinyl)ethanone N-oxides having the formula I or II: ##STR1## wherein R.sub.1 is hydrogen or lower alkyl; R.sub.2 and R.sub.3 are each hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy, or benzyloxy; R.sub.4 is halogen, hydroxy, lower alkyl, lower alkoxy, benzyloxy, ortho-amino, ortho-lower alkylamino, ortho-alkanoylamino or ortho benzoylamino; and R.sub.5 is hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy or benzyloxy; the pharmaceutically acceptable acid addition salts thereof, and a process for the preparation thereof, are described. The compounds of this invention are useful for the treatment of allergic conditions and for the treatment of hyperacidity.

REFERENCES:
patent: 4056619 (1977-11-01), Connor et al.
Chemical Abstracts vol. 85, abst. No. 177349b (1976) (abst. of Preuss et al).

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