1-Substituted-1-oxo-prostane-derivatives of the E, A and F serie

Details 1-Substituted-1-oxo-prostane-derivatives of the E, A and F serie 1-Substituted-1-oxo-prostane-derivatives of the E, A and F serie

1979-06-07

1981-10-27

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

542429, 2603409P, 568367, 568376, 568379, 568380, C07C17700

Patent

active

042975166

ABSTRACT:
The invention disclosed herein relates to pharmacologically active prostaglandin derivatives of the E, F, or A series having on the terminal methylene carbon of the alpha chain, a substituent selected from the group consisting of: ##STR1## wherein R is C.sub.1 to C.sub.6 alkyl, and phenyl or phenyl substituted with one or more substituents selected from the group consisting of C.sub.1 -C.sub.4 alkyl, OR.sub.16, SR.sub.16, F, or Cl, and R.sub.16 is C.sub.1 to C.sub.6 alkyl.

REFERENCES:
Samuelsson, Advances in Prostaglandin & Thromboxone Research V. pp. 483-491 (1977), Raven Press.

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