1-styrenesulphonyl-2-oxo-5-hydroxy pyrrolidines and their use fo

Details 1-styrenesulphonyl-2-oxo-5-hydroxy pyrrolidines and their use fo 1-styrenesulphonyl-2-oxo-5-hydroxy pyrrolidines and their use fo

1987-03-26

1989-03-07

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548542, A61K 3140, C07D20748

Patent

active

048107220

ABSTRACT:
The therapeutic compounds useful in the treatment of patients suffering from intellectual or nervous asthenias, memory failures or old age and excessive intellectual fatigue having the formula (I): ##STR1## in which R.sub.1 represents an alkyl radical, linear or branched, containing up to 8 carbons atoms, an acyl radical containing from 1 to 6 carbon atoms or a cycloalkyl radical containing from 3 to 6 carbon atoms and R represents an aryl radical containing up to 14 carbon atoms, unsubstituted or substituted, or a mono- or polycyclic heterocyclic radical, unsubstituted or substituted. Also, therapeutic compositions containing the compound, method of preparing the compound and method of use.

REFERENCES:
patent: 3423426 (1969-01-01), Kuhn
patent: 3686169 (1972-08-01), Coran et al.
Drugs of the Future, vol. 10, No. 12, 1985, pp. 972, 974.

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