1-Quinolinyl-pyrazolidine derivatives

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260283R, 260287F, 260288R, 260289R, 424258, C07D40104

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active

039962318

ABSTRACT:
The derivatives have the general formula ##STR1## in which X is a hydrogen atom or a methyl, phenyl or benzyl group; Y is a carbon chain comprising 2 to 6 carbon atoms, saturated or unsaturated, unsubstituted or substituted by alkyl, alkoxyl or halogen groups, said chain including if necessary, instead and in place of an aliphatic link, a carbonyl or alcohol group; Z is constituted by a hydrogen atom or defines at least an alkyl, alkoxyl or halogen group fixed at any position of the quinolinyl nucleus. They have high anti-inflammatory and analgesic activities.

REFERENCES:
weissberger et al., Chem. Abstr., vol. 39, col. 933, 1945.
Yasuyuki et al., Chem. Abstr., vol. 56, col. 3451b, 1962.
Golankiewicz, Chem. Abstr., vol. 60, col. 4107b, 1961.
Itai et al., Chem. Abstr., vol. 55, 27338c, (1961).

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