1-(Pyridazinyl)pyrazoline derivatives

Details 1-(Pyridazinyl)pyrazoline derivatives 1-(Pyridazinyl)pyrazoline derivatives

1982-03-02

1985-03-05

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544238, 544239, 548379, C07D23106, C07D23706, A61K 3150

Patent

active

045030561

ABSTRACT:
Described are compounds of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 independently of one another denote hydrogen or loweralkyl, X is hydroxy or amino, and Y is hydrogen, loweralkyl, loweralkoxy, benzyl or ##STR2## wherein W and Z independently of one another denote hydrogen, halo, loweralkyl, loweralkoxy, trifluoromethyl, acetamido, cyano, diloweralkylamino, phenoxy and loweralkylmercapto, and pharmaceutically acceptable salts thereof.
The compounds are effective as anti-inflammatory agents.

REFERENCES:
patent: 3657243 (1972-04-01), Quintilla
patent: 4224325 (1980-09-01), Szilagyi
patent: 4239901 (1980-12-01), Rainer
patent: 4251658 (1981-02-01), Szilagyi
Burger, Alfred, Medicinal Chemistry IVth, pp. 1224-1225.
Matsuura et al., Chem. Abst. 87: 68353u.
Burger, Medicinal Chemistry, Wiley Interscience, New York, (1970).
Szilagyi et al., "3(Pyrazol-1'-yl)Pyridazine Derivatives", Chem. Abst. 90: 152221.
Szilagyi et al., "3(Pyrazol-1'-yl)Pyridazine", Chem. Abst. 91: 107995.
Robertson et al., Medical Clinics of North America, vol. 65, No. 4, W. B. Saunders, Philadelphia, (1981), pp. 70-72.

Affiliated with

Also associated with

Rating

1-(Pyridazinyl)pyrazoline derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1-(Pyridazinyl)pyrazoline derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1-(Pyridazinyl)pyrazoline derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1734151