1-piperazinyl-2-butenes and -2-butynes

Details 1-piperazinyl-2-butenes and -2-butynes 1-piperazinyl-2-butenes and -2-butynes

1994-05-05

1995-08-08

Tsang, Cecilia

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544230, 544295, 544362, 544363, 544364, 544368, 544369, 544376, 548473, 548478, 548480, C07D20948, C07D40900

Patent

active

054400481

ABSTRACT:
Novel 1-piperazinyl-2-butenes and -2-butynes, intermediates and processes for the preparation thereof, and methods of treating psychoses utilizing compounds or compositions thereof are disclosed.

REFERENCES:
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patent: 5034392 (1991-07-01), Hrib
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Y.-H. Wu, et al., Journal of Medicinal Chemistry, 12, 876 (1969) published in the U.S. and entitled "Psychosedative Agent. N-(4-Phenyl-1-piperazinylalkyl)-Substituted Cyclic Amides".
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Y. Kojima, et al., Chemical Abstracts, vol. 110, p. 557, abstract 23914e (1989) published in the U.S. and entitled "Preparation of N-(piperazinylbutyl)imide Derivatives as Tranquilizers and Psychotropics".
J. P. Yevich, et al., Journal of Medicinal Chemistry, vol. 26, pp. 194 to 203 (Feb. 1983), published in the U.S. and entitled "Buspirone Analogues. 1. Structure-Activity Relationships in a Series of N-Aryl- and Heteroarypiperazine Derivatives".

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