1-Phenylindazol-3-one compounds

Details 1-Phenylindazol-3-one compounds 1-Phenylindazol-3-one compounds

1983-12-22

1985-08-27

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544364, 544371, C07D23156, C07D40306, A61K 31495

Patent

active

045379750

ABSTRACT:
Compounds corresponding to the formula: ##STR1## wherein R.sub.1 and R.sub.3 each represent hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl; R.sub.2 and R.sub.4 each represent hydrogen, halogen, lower alkyl or lower alkoxy; Z represents an alkylene radical with 2 to 6 carbon atoms and Y" is halogen, hydroxyl, lower alkanesulphonyl, benzenesulphonyl, or lower alkyl or halogen substituted benzenesulphonyl, and acid addition salts thereof, with the proviso the Y" is other than chlorine if R.sub.1, R.sub.2, R.sub.3 and R.sub.4 each are hydrogen and Z is ethylene or propylene. The claimed compounds are useful intermediates in the synthesis of 1-phenyl-2-[(4-substituted piperazinyl) alkyl]-1,2-dihydro-3H-indazol-3-ones which exhibit antiallergic activity.

REFERENCES:
Baiocchi et al. (I), Chem. Abst. 72, 90367p, (1970).
Baiocchi et al. (II), Synthesis, No. 9, pp. 633-648, (1978).
Palazzo et al., J. Med. Chem, 9, pp. 38-41, (1966).

Affiliated with

Also associated with

Rating

1-Phenylindazol-3-one compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1-Phenylindazol-3-one compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1-Phenylindazol-3-one compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2002586