1-phenyl substituted-1H, 3H-thiazole [3,4-a] benzimidazoles and

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548151, A61K 31425, C07D51304

Patent

active

052179842

ABSTRACT:
1-Phenyl substituted-1H,3H-thiazole [3,4-a] benzimidazoles are prepared by reaction of o.phenilendiamine with a substituted benzaldehyde and with 2-mercaptoacetic acid. The new compounds are antiviral products.

REFERENCES:
patent: 3665007 (1972-05-01), Haugwitz et al.
patent: 3732240 (1973-05-01), Haugwitz et al.
patent: 4464384 (1984-08-01), Murase et al.
Chimirri et al., Synthesis, No. 3, pp. 244-246 (1988).
"An Unexpected Reaction Between 2,3-dihydro-2,2,4-trimethyl-1H-1,5-benzo diazepine and Mercaptoacetic Acid", A. Chimirri et al., Chemical Abstracts, vol. 108, No. 9, Feb. 29, 1988, p. 680.

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