1-phenyl-4-benzylpiperazines dopamine receptor subtype...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C544S392000

Reexamination Certificate

active

07101887

ABSTRACT:
Disclosed are compounds of the formula:or the pharmaceutically acceptable addition salts thereof wherein:R1is halogen or C1–C4alkyl; andR2and R3are the same or different and represent hydrogen, halogen, C1–C4alkyl, C1–C4alkoxy, alkylthio, hydroxy, amino, mono(C1–C4)alkylamino, di(C1–C4)alkylamino, orR2and R3together represent a 4 carbon alkenylene moiety that together with the phenyl ring to which they are attached form a naphthyl moiety,which compounds are useful in the treatment of neuropsycological diseases such as schizophrenia, psychotic depression and mania.

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