1-Phenyl-4-amino-cyclohex-2-ene-1-carboxylic acid ethyl esters

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2602472B, 260268R, 260268C, 260268PH, 26029381, 26029382, 260456R, 260456P, 260469, 260471R, 260473R, 424248, 424250, 424267, 424309, C07C10138

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active

039578518

ABSTRACT:
The invention relates to 1-phenyl-4-amino-cyclohex-2-ene-1-carboxylic-acid-esters of the general formula I ##SPC1##
wherein R.sub.1 and R.sub.2 may be the same or different and may be H, alkyl, hydroxyalkyl, alkenyl, preferably with 1 to 4 C-atoms, aralkyl which may be bonded to each other, in which connection the heterocyclic system formed may be substituted further by the OH-- group and where attachment takes place by an oxygen or a nitrogen atom, if desired, which in its turn carries an H, alkyl with 1 to 4 C-atoms, aryl which may be substituted by chlorine, preferably in 3 or 4-position, and by methoxy, preferably in 2 or 4-position, acyl, preferably alkanoyl with 1 to 4 C-atoms, and aroyl, or aralkyl, and R.sub.3 represents an alkyl radical with 1 to 4 C-atoms, the salts thereof and quarternary ammonium compounds, and a process for their preparation. These compounds have analgesic and neuroleptic properties.

REFERENCES:
patent: 3557127 (1971-01-01), Satzinger
C.A. 74: 91,163x (1971) Satzinger et al.

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