1-Phenyl-2(1H,3H)-indolone psychotherapeutic agents

Details 1-Phenyl-2(1H,3H)-indolone psychotherapeutic agents 1-Phenyl-2(1H,3H)-indolone psychotherapeutic agents

1987-08-03

1989-11-07

Sneed, H. M. S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548466, C07D20934

Patent

active

048793914

ABSTRACT:
Certain substituted 1-phenyl-3-(aminoalkylidene)-2(1H,3H)-indolones are highly potent gabaergic agents, valuable in the treatment of individuals suffering from schizophrenia or reversing the side effects of a previously or concurrently administered neuroleptic agent; or in the treatment of epilepsy. A wider class of substituted 1-phenyl-3-(aminoalkylidene)-2(1H,3H)-indolones, together with 1-phenyl-3-(2-pyrrolidinylidiene-2(1H,3H)-indolones, and homologs thereof, are valuable in the treatment of anxiety.

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Latrell et al., CA 89:179858y, 1978.
Meyers et al., Review of Medicinal Pharmacology, 4th Ed., Lange Medical Publications, 1974, p. 149.

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