1(p-Chlorobenzoyl)-5-methoxy-2-methyl indole-3-acetic acid-3-oxo

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...

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Details

26032613A, A61K 3140, C07D20926

Patent

active

042774896

ABSTRACT:
This invention relates to a derivative of 1-(p-chlorobenzoyl)-5-methoxy-2-methyl indole-3-acetic acid with 3-oxo-1-isobenzofuranyl, linked by an ester bond, more particularly to 1-(p-chlorobenzoyl)-5-methoxy-2-methyl indole-3-acet-3-oxo-1-isobenzofuranyl ester, as well as to its preparation and therapeutical use as an analgesic and anti-inflammatory agent.
Said compound is prepared by reacting equi-molecular amounts of 1-(p-chlorobenzoyl)-5-methoxy-2-methyl indole-3-acetic acid and bromophthalide a few hours at room temperature, under a mild stirring, in the presence of a base.

REFERENCES:
patent: 3103515 (1963-09-01), Zaugg et al.

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