1-Oxo-1H-6-piperidinopyrimido[1,2-a]quinoline-2-carboxylic acids

Details 1-Oxo-1H-6-piperidinopyrimido[1,2-a]quinoline-2-carboxylic acids 1-Oxo-1H-6-piperidinopyrimido[1,2-a]quinoline-2-carboxylic acids

1975-07-10

1977-03-29

Coughlan, Jr., Paul M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260251A, 424251, C07D40104

Patent

active

040148815

ABSTRACT:
As antiulcer agents, a series of 1-oxo-1H-6-substituted pyrimido[1,2-a]quinoline-2-carboxylic acids and esters of the formula ##STR1## wherein R.sub.1 is alkoxy having from one to two carbon atoms or piperidino; and R.sub.2 is hydrogen or alkyl having from one to four carbon atoms; the pharmaceutically acceptable acid addition salts of those compounds wherein R.sub.1 is piperidino, and the pharmaceutically acceptable cationic salts of those compounds wherein R.sub.2 is hydrogen.

REFERENCES:
richardson et al., J. Med. Chem., vol. 15 (1972), pp. 1203-1206.

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