1-Oxa-2,6-disilacyclohexane-4-carboxamides

Details 1-Oxa-2,6-disilacyclohexane-4-carboxamides 1-Oxa-2,6-disilacyclohexane-4-carboxamides

1982-10-12

1983-11-15

Shaver, Paul F.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

556419, 548495, C07F 708, C07F 710

Patent

active

044155603

ABSTRACT:
Silicon-containing amides, e.g., N-[1'-phenyl-2'-(4"-methylphenyl)ethyl]-2,2,6,6-tetramethyl-1-oxa-2,6-disi lacyclohexane-4-carboxamide, are useful as anti-atherosclerotic agents. The amides are obtainable by acylation of a primary amine (the substituents on the amine being of the aralkyl phenyl, tryptophanyl, benzocycloalkyl-type) with a corresponding silicon-containing carboxylic acid (or active form thereof).

REFERENCES:
patent: 2838423 (1958-06-01), Gilkey
patent: 2919173 (1959-12-01), Roff
patent: 4297349 (1981-10-01), Barcza

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