1-oxa-1-dethia-cephalosporin compounds and antibacterial agent c

Details 1-oxa-1-dethia-cephalosporin compounds and antibacterial agent c 1-oxa-1-dethia-cephalosporin compounds and antibacterial agent c

1985-03-01

1987-02-24

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544 90, A01N 4390, C07D49804

Patent

active

046457690

ABSTRACT:
The subject invention includes a 1-oxa-1-dethia-cephalosporin compound represented by the general formula (1) ##STR1## wherein R.sup.1 is a group of the formula: ##STR2## where R.sup.5 is a methyl group, an ethyl group, a carboxymethyl group or a 2-carboxy isopropyl group, or R.sup.1 is a group of the formula: ##STR3## where R.sup.6 is a hydrogen atom, a 4-ethyl-2,3-dioxopiperazine-1-yl group, a 3,4-dihydroxy phenyl group or a 5- and 6-membered heterocyclic radical having 2 ring nitrogens as the sole hetero substituent in the ring and having at least one hetero group on the carbon adjacent to the ring nitrogens.

REFERENCES:
patent: 4226864 (1980-10-01), Narisada et al.
patent: 4226866 (1980-10-01), Christensen et al.
patent: 4307116 (1981-12-01), Large et al.
patent: 4366316 (1982-12-01), Yoshioka et al.
patent: 4438114 (1984-03-01), Boberg et al.
patent: 4504477 (1985-03-01), O'Callaghan et al.
patent: 4534898 (1985-08-01), Shibahara et al.
Morin et al., Chemistry and Biology of .beta.-Lactam Antibiotics, vol. 2 (1982) Academic Press, New York, pp. 1-98.

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