1-Nitro-9-alkylaminoalkylaminoacridines and salts thereof

Details 1-Nitro-9-alkylaminoalkylaminoacridines and salts thereof 1-Nitro-9-alkylaminoalkylaminoacridines and salts thereof

1977-02-23

1979-02-13

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424257, C07D21912, A61K 3147

Patent

active

041395310

ABSTRACT:
1-Nitro-9-alkylaminoalkylaminoacridins and their salts, as well as a method for obtaining these compounds, is described. The 1-nitro-9-alkylaminoalkylaminoacridines have the formula 1, ##STR1## wherein R is methyl, ethyl, propyl, isopropyl, butyl, isobutyl, isopentyl, benzyl or cyclohexyl, whereas n is equal to 2 or 3. The salts are those derived from mineral acids or organic acids. These compounds have anti-neoplastic activity.

REFERENCES:
patent: 1962277 (1934-06-01), Jensch et al.
Konopa et al., Chem. Abstracts, v. 71, 37,302s (1969).
Ledochowski, Chem. Abstracts, v. 67, 64,226u (1967).

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