1-(N-Substituted carbamoyl)-5-fluorouracil derivatives and the c

Details 1-(N-Substituted carbamoyl)-5-fluorouracil derivatives and the c 1-(N-Substituted carbamoyl)-5-fluorouracil derivatives and the c

1983-01-05

1985-02-05

Coughlan, Jr., Paul M.

Abrasive tool making process, material, or composition

544311, A61K 31505, C07D23955

Patent

active

044978154

ABSTRACT:
A 1-(N-substituted carbamoyl)-5-fluorouracil derivative represented by the following general formula: ##STR1## R is a 4-alkoxycyclohexyl group-containing radical which is 2,3,4-trimethoxycyclohexcylethyl, 2,3,4-trimethoxycyclohexyl, 2,4-dimethoxycyclohexylmethyl, 3,4-dimethoxycyclohexylethyl, 2,4-dimethoxycyclohexyl, 2,4,5-trimethoxycyclohexyl, 3,4-dimethoxycyclohexylmethyl, 3,4,5-trimethoxycyclohexyl, 4-ethoxycyclohexyl or 4-ethoxycyclohexylmethyl. The compounds are carcinostatic agents. The compounds are used in a therapeutically effective amount in the presence of a carrier.

REFERENCES:
patent: 4032524 (1977-06-01), Ozaki et al.
patent: 4349552 (1982-09-01), Takaya et al.
Chemical Abstracts, Ozaki et al., 90:6415u and 6416v, 1979.

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