1-N-(.omega.-amino-.alpha.-hydroxyalkanoyl) derivatives of 4'-de

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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424180, A61K 3171, C07H 1522

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active

041817974

ABSTRACT:
1-N-(.omega.-Amino-.alpha.-hydroxyalkanoyl) derivatives of 4'-deoxy-6'-N-methylkanamycin A are prepared by multi-step processes beginning with 1,3-ureidokanamycin A. The compounds are potent antibacterial agents.

REFERENCES:
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patent: 3886138 (1975-05-01), Naito et al.
patent: 3886139 (1975-05-01), Naito et al.
patent: 3904597 (1975-09-01), Naito et al.
patent: 3925353 (1975-12-01), Umezawa et al.
Umezawa et al., "Jour. of Antibiotics", vol. 27, 1974, pp. 722-725.
Naito et al. "Jour. of Antibiotics", vol. 27, 1974, pp. 838-850.

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