1-N-(.omega.-Amino-.alpha.-hydroxyalkanoyl-2',3'-dideoxykanamyci

Details 1-N-(.omega.-Amino-.alpha.-hydroxyalkanoyl-2',3'-dideoxykanamyci 1-N-(.omega.-Amino-.alpha.-hydroxyalkanoyl-2',3'-dideoxykanamyci

1984-08-10

1985-10-15

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 137, 536 138, A61K 3171, C07H 1522

Patent

active

045474923

ABSTRACT:
1-N-(L-3-amino-2-hydroxypropionyl)-2',-3'-dideoxykanamycin A and 1-N-(L-4-amino-2-hydroxybutyryl)-2',3'-dideoxykanamycin A are now provided which each is a new compound useful as antibacterial agent. The new compounds each is produced by acylating the 1-amino group of 2',3'-dideoxykanamycin A with L-3-amino-2-hydroxypropionic or L-4-amino-2-hydroxybutyric acid.

REFERENCES:
patent: 4104372 (1978-08-01), Umezawa et al.
patent: 4160082 (1979-07-01), Million et al.
patent: 4298727 (1981-11-01), Umezawa et al.

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