1-N-Kanamycin derivatives

Details 1-N-Kanamycin derivatives 1-N-Kanamycin derivatives

1978-07-14

1979-12-11

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 536 17R, A61K 3171, C07H 1522

Patent

active

041784375

ABSTRACT:
3-N-formyl derivatives of 3",6'-di-N-acyl-kanamycin A and 2',3",6'-tri-N-acyl-kanamycin B, process for their preparation, and their use as intermediates for production of antibacterially active 1-N-(substituted) derivatives of kanamycins A and B by alkylation and subsequent removal of the formyl and acyl groups.

REFERENCES:
patent: 3350387 (1967-10-01), Vanderhaeghe
patent: 4029882 (1977-06-01), Wright
patent: 4044123 (1977-08-01), Daniels et al.
patent: 4065615 (1977-12-01), Horii et al.

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