1-(N-formylamino)-2,4-dicyanobutane and a process for its produc

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitriles

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C07C12143

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049355341

ABSTRACT:
This invention relates to the novel compound 1-(N-formylamino)-2,4-dicyanobutane, which is useful as an intermediate, for example, in the preparation of -aminomethyl glutamic acid. This invention further relates to a process for the production of 1-(N-formylamino)-2,4-dicyanobutane by the reaction of 2,4-dicyano-1-butene and formamide in the presence of 4-aminopyridine derivative.

REFERENCES:
patent: 4701546 (1987-10-01), Bewert et al.
patent: 4845261 (1989-07-01), Fuentes
Handbook of Chemistry and Physics 1975, CRC Press, pp. D-127 and D-128.
Holfe, Steglich, and Vorbruggen, Angew, Chem. Int. Ed. Engl. 17, 569-583, (1978).
J. Biol. Chem., 251, 2263-2270 (1976)-(Chem. Abstract Attached).

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