1-N(.alpha.Hydroxy-.omega.-aminoalkanoyl) derivatives of 5,3',4'

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

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536 137, 536 138, A61K 3171, C07H 1522

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active

044105169

ABSTRACT:
New antibacterial compounds are provided, including a 1-N-(.alpha.-hydroxy-.omega.-aminoalkanoyl)-5,3',4'-trideoxykanamycin B; a 1-N(.alpha.-hydroxy-.omega.-aminoalkanoyl)-5,3',4',641 -tetradeoxykanamycin B; and a 1-N-(.alpha.-hydroxy-.omega.-aminoalkanoyl)-5,3',4'-trideoxy-6'-N-methylka namycin B; as well as 5,3',4',6"-tetradeoxykanamycin B and 5,3',4'-trideoxy-6'-N-methylkanamycin B.

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patent: 4147861 (1979-04-01), Umezawa et al.

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