1-N(.alpha.Hydroxy-.omega.-aminoalkanoyl) derivatives of 5,3',4'

Details 1-N(.alpha.Hydroxy-.omega.-aminoalkanoyl) derivatives of 5,3',4' 1-N(.alpha.Hydroxy-.omega.-aminoalkanoyl) derivatives of 5,3',4'

1981-07-21

1983-10-18

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

536 137, 536 138, A61K 3171, C07H 1522

Patent

active

044105169

ABSTRACT:
New antibacterial compounds are provided, including a 1-N-(.alpha.-hydroxy-.omega.-aminoalkanoyl)-5,3',4'-trideoxykanamycin B; a 1-N(.alpha.-hydroxy-.omega.-aminoalkanoyl)-5,3',4',641 -tetradeoxykanamycin B; and a 1-N-(.alpha.-hydroxy-.omega.-aminoalkanoyl)-5,3',4'-trideoxy-6'-N-methylka namycin B; as well as 5,3',4',6"-tetradeoxykanamycin B and 5,3',4'-trideoxy-6'-N-methylkanamycin B.

REFERENCES:
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patent: 3929762 (1975-12-01), Umezawa et al.
patent: 3940382 (1976-02-01), Umezawa et al.
patent: 4044123 (1977-08-01), Daniels et al.
patent: 4104372 (1978-08-01), Umezawa et al.
patent: 4107424 (1978-08-01), Umezawa et al.
patent: 4147861 (1979-04-01), Umezawa et al.

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