1-methylindazole-3-carboxylic acid process

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D23156

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active

049469665

ABSTRACT:
A process for the preparation of a compound of formula (I): ##STR1## which comprises the reactive of a methylating agent with a compound of formula (IV): ##STR2## in a polar solvent in which is dissolved an alkali metal alkoxide, in an inert atmosphere.

REFERENCES:
patent: 3736332 (1973-05-01), Butula
Wiley, Pyrazoles, Pyrazolines, Pyrazolidines, Indazoles and Condensed Rings, (1967), pp. 309-313.
Auwers et al., Chemical Abstracts, vol. 14 (1920), pp. 3662-3663.
V. Rousseau et al., "Structure and Ultraviolet Absorption Spectra of Indazole, 3-Substituted Indazole and Some of Their Derivatives", Journal of the American Chemical Society, 72, pp. 3047-3051 (1950).

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