Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1974-08-23
1976-05-04
Winters, Sherman D.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
26029368, 26029369, 26029373, 26029383, 260296R, 2603265D, 2603265S, 2603265SM, 2603265SF, 2603265M, 424263, 424267, 424274, C07D21114
Patent
active
039547760
ABSTRACT:
1-[Methylated piperidino (and pyrrolidin-1-yl)]-3-(substituted phenoxy)-2-propanols of the formula: ##SPC1##
Wherein R is a 2-thienylmethyl group, a 2-pyridylmethyl group, a 2-pyridyl group, a tetrahydrofurfuryloxy group, a furfuryloxy group, a 2-thienylmethoxy group, a 2-pyridyloxy group or a group of the formula R.sup.5 --X--A--O-- wherein R.sup.5 is a lower alkyl group, X is --O--, --S-- or --SO.sub.2 --, and A is a lower alkylene group or a --CH.sub.2 --C.ident.C--CH.sub.2 -- group, R.sup.1 is a hydrogen atom, a lower alkyl group or a halogen atom, R.sup.2, R.sup.3 and R.sup.4 are each a hydrogen atom or a methyl group, and n is zero or 1, and pharmaceutically acceptable acid addition and quarternary ammonium salts thereof are disclosed. They exhibit antiarrhythmic action, local anaesthetic action, analgesic action and gastric juice secretion inhibiting action.
REFERENCES:
patent: 3723476 (1973-03-01), Nakanishi et al.
Chihara Yasuaki
Fukuzawa Sogo
Muro Tomio
Nakao Tohru
Ogawa Kiyoshi
Winters Sherman D.
Yoshitomi Pharmeceutical Industries, Ltd.
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