1-Methyl-5-p-methylbenzoylpyrrole-2-acetamidoacetanilides with a

Details 1-Methyl-5-p-methylbenzoylpyrrole-2-acetamidoacetanilides with a 1-Methyl-5-p-methylbenzoylpyrrole-2-acetamidoacetanilides with a

1984-07-26

1986-02-04

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548539, C07D207323

Patent

active

045686904

ABSTRACT:
The anilide derivates of 1-methyl-5-p-methylbenzoylpyrrole-2-acetamidoacetic acid are described, with general formula ##STR1## in which R, R', R" and R"' may be hydrogen, halogen, alkyl, alkoxyl or a trifluoromethyl group. The compounds show useful antiinflammatory analgesic, anti-pyretic and antiplatelet aggregant activities.

REFERENCES:
patent: 3952012 (1976-04-01), Carson
patent: 4070368 (1978-01-01), Carson
patent: 4200645 (1980-04-01), Goudie
patent: 4379793 (1983-04-01), Badia
patent: 4396626 (1983-08-01), Ward et al.
patent: 4434175 (1984-02-01), Doherty et al.
patent: 4521538 (1985-06-01), Baglioni
Abstract of Japan Application 0144256; Sep. 6, 1982.

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