1-isopropyl-4[(4-tetrahydro-1-naphthoyloxy phenyl)(alkylene)-car

Details 1-isopropyl-4[(4-tetrahydro-1-naphthoyloxy phenyl)(alkylene)-car 1-isopropyl-4[(4-tetrahydro-1-naphthoyloxy phenyl)(alkylene)-car

1985-10-17

1986-10-28

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544398, 544399, 544400, 544402, 514255, C07D24104, A61K 31495

Patent

active

046200053

ABSTRACT:
Phenyl tetrahydronaphthylcarboxylate of the formula: ##STR1## wherein A is a direct bond, or a lower alkylene, vinylene or imino group; B is a direct bond, a lower alkylene or --NH-lower alkylene group, or an --OCH.sub.2 CO-- residual group; and R is a lower alkyl group, with the proviso that A and B are not direct bonds simultaneously, and A, B and R are not a lower alkylene group, a direct bond and a methyl group, respectively, at the same time, are effectively useful as chymotrypsin inhibitors.

REFERENCES:
patent: 3846430 (1974-11-01), de Antoni et al.
patent: 4443603 (1984-04-01), Fujii et al.
Kohjin Co., Ltd., Chem. Abst., 99-38809c.
Kowa Co., Ltd., Chem. Abst., 96-180955d.

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