Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing
Patent
1980-04-03
1981-09-22
Trousof, Natalie
Organic compounds -- part of the class 532-570 series
Organic compounds
Oxygen containing
568379, 568380, 568367, 568631, 568644, 568645, 568660, 568664, 568669, 568670, 568807, 568816, 568838, 568822, 568376, 560255, 560231, 560 65, 560 64, 560 73, 560106, 560107, 424308, 424311, 424331, 424343, 424341, 424339, C07C 3506, C07C 49597, C07C 49798
Patent
active
042911753
ABSTRACT:
Prostaglandin analogs are disclosed that have the .alpha.-chain terminating with the group --CH(OR')OR" wherein R' and R" are the same or different and are hydrogen, C.sub.1 to C.sub.4 alkanoyl or optionally substituted benzoyl, the substituents selected from the group C.sub.1 to C.sub.4 alkyl, C.sub.1 to C.sub.4 alkoxy, halo and trifluoromethyl. These compounds are useful as hypotensive agents, gastric secretory and platelet aggregation enhibitors and bronchodilators.
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Bently, Chem. Soc. Rev., #2, pp. 29-70, (1973).
Floyd, Jr. Middleton B.
Wissner Allan
American Cyanamid Company
Johnson Norton S.
Reamer James H.
Trousof Natalie
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