1-Hydroxymethyl-1-oxo-prostane derivatives of the E series

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

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C07C 49395

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active

042999880

ABSTRACT:
The invention disclosed herein relates to pharmacologically active prostaglandin derivatives of the E series having on the terminal methylene carbon of the alpha chain a hydroxymethylketo substituent ##STR1##

REFERENCES:
patent: 3751463 (1973-08-01), Caton et al.
patent: 4251466 (1981-02-01), Axen
Bergstom et al., J. Biol. Chem., vol. 238, 355 (1963).
Horton, Experientia, vol. 21, 113 (1965).

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