1-Hydroxyalkanamine pyrano(3,4-b)indole compositions and use the

Details 1-Hydroxyalkanamine pyrano(3,4-b)indole compositions and use the 1-Hydroxyalkanamine pyrano(3,4-b)indole compositions and use the

1979-05-14

1980-11-25

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

42424857, 424267, 424274, A61K 31535, A61K 3140

Patent

active

042359015

ABSTRACT:
Indole derivatives characterized by having a 1,3,4,9-tetrahydropyrano-[3,4-b]indole or 1,3,4,9-tetrahydrothiopyrano[3,4-b]indole nucleus with a hydroxyalkanamine or lower alkoxyalkanamine substituent and a lower alkyl group at position 1 are disclosed. The nucleus is optionally further substituted at position 9 and on the aromatic ring. The derivatives are useful diuretic agents, and methods for their preparation and use are also disclosed.

REFERENCES:
patent: 3778449 (1973-12-01), Jirkovsky et al.
patent: 3910954 (1975-10-01), Jirkovsky et al.

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