1-Hydroxyalkanamine pyrano(3,4-b)indole compositions and use the

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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42424857, 424267, 424274, A61K 31535, A61K 3140

Patent

active

042359015

ABSTRACT:
Indole derivatives characterized by having a 1,3,4,9-tetrahydropyrano-[3,4-b]indole or 1,3,4,9-tetrahydrothiopyrano[3,4-b]indole nucleus with a hydroxyalkanamine or lower alkoxyalkanamine substituent and a lower alkyl group at position 1 are disclosed. The nucleus is optionally further substituted at position 9 and on the aromatic ring. The derivatives are useful diuretic agents, and methods for their preparation and use are also disclosed.

REFERENCES:
patent: 3778449 (1973-12-01), Jirkovsky et al.
patent: 3910954 (1975-10-01), Jirkovsky et al.

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