1-Hydroxy-1-[(4'-hydroxy-3'aminosulfonamido)-phenyl]-2-amino-eth

Details 1-Hydroxy-1-[(4'-hydroxy-3'aminosulfonamido)-phenyl]-2-amino-eth 1-Hydroxy-1-[(4'-hydroxy-3'aminosulfonamido)-phenyl]-2-amino-eth

1974-03-21

1977-07-26

Wyman, Daniel E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424321, 26050119, C07C14380, A61K 3118

Patent

active

040383148

ABSTRACT:
Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen or methyl, and R.sub.2 is phenoxy-(alkyl of 2 to 3 carbon atoms), phenyl-(alkyl of 4 to 5 carbon atoms), hydroxyphenyl-(alkyl of 3 to 5 carbon atoms), or naphthyl-(alkyl of 4 to 5 carbon atoms);
And their non-toxic, pharmacologically acceptable acid additions salts; the compounds as well as the salts are useful as dilators of the peripheral blood vessels, as cardiotonics and as broncholytics.

REFERENCES:
patent: 3574741 (1971-04-01), Gould et al.
patent: 3701808 (1972-10-01), Hartley et al.
patent: 3711545 (1973-01-01), Kaiser et al.
patent: 3804834 (1974-04-01), Mentrup et al.
patent: 3875233 (1975-04-01), Bastian et al.
Medicinal Chemistry, Burger, Ed., 3rd Ed., Part II, pp. 1253-1257 (1969).

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