1-hydroxy-1,1-diphosphonic acids and cytostatic use thereof

Details 1-hydroxy-1,1-diphosphonic acids and cytostatic use thereof 1-hydroxy-1,1-diphosphonic acids and cytostatic use thereof

1985-07-10

1986-08-26

Evans, J. E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

2605025C, C07F 938, A61K 31135, A61K 31085, A61K 3110

Patent

active

046083685

ABSTRACT:
1-hydroxy-1,1-diphosphonic acid compounds corresponding to the following general formula ##STR1## in which R and R.sub.1 represent hydrogen or methyl,

REFERENCES:
patent: 3202579 (1965-08-01), Berth et al.
patent: 3617342 (1971-11-01), Kandler et al.
patent: 3617576 (1971-11-01), Korst
patent: 3668138 (1972-06-01), Hoover et al.
patent: 3816518 (1974-06-01), Kerst
patent: 4098814 (1978-07-01), Sommer et al.
patent: 4230700 (1980-10-01), Francis
patent: 4371527 (1983-02-01), Bentzen et al.
patent: 4416877 (1983-11-01), Bentzen et al.
patent: 4503049 (1985-03-01), Biere et al.
Arch. Pharm. (Weinheim) 311, 184-195 (1978).

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