Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1986-08-15
1987-04-14
Jiles, Henry R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
546120, C07D47104
Patent
active
046580298
ABSTRACT:
This invention claims compounds having the formulae ##STR1## where R.sub.1 is hydrogen, loweralkyl, arylloweralkyl, aryl or heteroaryl; R.sub.2 is hydrogen or loweralkyl; R.sub.3 is loweralkyl, loweralkoxyloweralkyl, cycloalkyl, arylloweralkyl or heteroarylmethyl; R.sub.4 is hydrogen or loweralkyl; and Z is O, S, NR.sub.5 or CH.dbd.N, R.sub.5 being loweralkyl, phenylloweralkyl or benzensulfonyl. These compounds are useful as intermediates for synthesizing 6H-isoxazolo[5,4-d]pyrazolo[3,4-b]pyridines which in turn are useful as analgesic and hypotensive agents.
Hoechst-Roussel Pharmaceuticals Inc.
Ikeda Tatsuya
Jiles Henry R.
Richter J.
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