1-heteroazolyl-1-heterocyclyl alkane derivatives and their use a

Details 1-heteroazolyl-1-heterocyclyl alkane derivatives and their use a 1-heteroazolyl-1-heterocyclyl alkane derivatives and their use a

1995-06-02

1997-03-04

McKane, Joseph

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514361, 514362, 514363, 514364, 514372, 514374, 514378, 514381, 514383, 514385, 514396, 514399, 514400, 514403, 514406, 514408, 514423, 514427, 514428, A61K 3141, A61K 3142, A61K 31425

Patent

active

056079567

ABSTRACT:
The present invention relates to novel heterocyclic compounds having the general formula (1) ##STR1## geometric and optical isomers and racemates thereof where such isomers exist, as well as pharmaceutically acceptable acid addition salts thereof and solvates thereof;
having therapeutic activity, processes and intermediates for their preparation, pharmaceutical formulations containing said compounds and the medicinal use of said compounds.

REFERENCES:
patent: 5068237 (1991-11-01), Hobbs
Dondoni et al., "Synthesis of (Trimethylsilyl) thiazoles and Reactions with Carbonyl Compounds. Selectivity Aspects and Synthetic Utility," J. Org. Chem. vol. 53 (1988).
Patent Abstacts of Japan, vol. 13, No. 592, C-671, abstract of JP, A, 1-249760 (Yamaha Corp.), Oct. 5, 1989.
CA 101:191771p (1,3-Dialkyl-5-amino-1H-pyrazol-4-yl)arylmethanones. A series . . . depressants. Butler et al., p. 756, 1984.
CA 116:106294c Preparation . . . psychoanaleptics Hobbs, p. 779, 1992.
CA 119:271158f (Amidazolylalkyl) . . . agonists. Shih et al., p. 998, 1993.

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