1-Heteroarylsulphonyl-2-imino-imidazolidines

Details 1-Heteroarylsulphonyl-2-imino-imidazolidines 1-Heteroarylsulphonyl-2-imino-imidazolidines

1974-07-15

1976-03-02

Love, Ethel G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260243R, 260248AS, 260248R, 260250A, 260250R, 2602564R, 2602948F, 260302A, 260302D, 260302H, 260307G, 260307H, 260307R, 260308A, 260308D, 260308R, 260309, 2603322R, 424246, 424249, 424250, 424263, 424269, 424270, 424272, 424273, C07D 4934

Patent

active

039418049

ABSTRACT:
Compounds of the class of 1-heteroarylsulphonyl-2-imino-imidazolidines which are substituted in the 3-position by an aliphatic or cycloaliphatic hydrocarbon radical, especially a cycloalkyl radical, and their pharmaceutically acceptable acid addition salts have valuable pharmacological properties. In particular, they possess hypoglycaemic activity and can be used for the treatment of hyperglycaemia in mammals. A specific embodiment is 1-[5-(2-butyramido-ethyl)-2-thienylsulphonyl]-2-imino-5-cyclohexyl-imidazo lidine.

REFERENCES:
patent: 3538035 (1970-11-01), Dietrich
patent: 3812144 (1974-05-01), Dietrich

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