1-fluoro, 4-fluoro, and 1,4-difluoro anthracycline anticancer an

Details 1-fluoro, 4-fluoro, and 1,4-difluoro anthracycline anticancer an 1-fluoro, 4-fluoro, and 1,4-difluoro anthracycline anticancer an

1985-03-20

1987-09-29

Brown, J. R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

260365, C07H 1524

Patent

active

046970053

ABSTRACT:
Compounds represented by the formula (I) ##STR1## wherein R is hydrogen or hydroxyl, one of X and Y is fluorine and the other is hydrogen or both X and Y are fluorine, and Su is a hydrogen atom or a sugar moiety; where Su is a sugar moiety, the compounds are useful anticancer antibiotics; pharmaceutical preparations containing the antibiotics and a method for inhibiting the growth of mammalian tumors are also disclosed.

REFERENCES:
patent: 4046878 (1977-09-01), Patelli et al.
patent: 4427664 (1984-01-01), Hordon et al.

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