1-dethia-2-thia-cephalosporanic acids

Details 1-dethia-2-thia-cephalosporanic acids 1-dethia-2-thia-cephalosporanic acids

1988-02-08

1990-03-13

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540214, C07D41712, A61K 3154

Patent

active

049083597

ABSTRACT:
1-dethia-2-thia-cephalosporanic acids of the formula ##STR1## wherein R is selected from the group consisting of ##STR2## R.sub.b --NH--and ##STR3## R.sub.a is an organic radical R.sub.i and R.sub.j are individually selected from the group consisting of hydrogen, aliphatic, aromatic and heterocycle or taken together with the nitrogen atom form an optionally substituted heterocycle, R.sub.b is optionally substituted carbocyclic or heterocyclic aryl, R.sub.1B is --[CH.dbd.CH].sub.n1 --CH.sub.2 --S--R.sub.m, n.sub.1 is 0, 1 or 2, Rm is an unsaturated radical including a positively charged and doubly bonded nitrogen atom and bonded to the sulfur atom through a carbon atom, R.sub.4 is hydrogen or methoxy, n.sub.2 is 0, 1 or 2 and A is selected from the group consisting of hydrogen, alkali metal ion, or alkaline earth metal ion, magnesium ion, ammonium ion, an organic amine base and an ester group or --COOA is --COO.sup.- and their non-toxic, pharmaceutically acceptable acid addition salts, having antibiotic activity.

REFERENCES:
patent: 4476124 (1984-10-01), Heymes et al.

Affiliated with

Also associated with

Rating

1-dethia-2-thia-cephalosporanic acids does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1-dethia-2-thia-cephalosporanic acids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1-dethia-2-thia-cephalosporanic acids will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-51325